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Microgest 100mg 10 Capsules/Strip


Microgest 100mg 10 Capsules/Strip

 

Microgest 100mg (Progesterone)


Product Name
Microgest 100mg 10 Capsules/Strip
Active Ingredient
Micronized progesterone
Manufacturer
Martin & Harris
Product Type
Progestogen (micronized progesterone)
Product expiry date we are currently shipping
Jul 2015
Packaging & Product
Microgest 100mg capsules in blister strips of 10 Capsules
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Product Price List REMEMBER SHIPPING IS FREE!

Microgest 100mg 50 Capsules
$0.92 per Capsule
| $46.00 (USD) 
Microgest 100mg 100 Capsules
$0.81 per Capsule
| $80.50 (USD) 
Microgest 100mg 150 Capsules
$0.81 per Capsule
| $120.75 (USD) 
Other Strengths
Microgest 200mg  (Progesterone)
Microgest 200mg (Progesterone)
$55.20 (USD)
From $0.84 per Capsule


Microgest contains micronized progesterone 100mg which when added to oestrogen hormone replacement therapy (HRT) reduce the risk of postmenopausal endometrial cancer. It is also to induce breast development in transgender hormone therapy.

Microgest general information

What is Microgest used for?

Microgest 100mg capsules are used as part of a hormone replacement therapy (HRT) regime, to reduce the risk of endometrial (uterine) cancer, which can develop in response to a oestrogen only HRT. Microgest 100mg capsules counteract the stimulating effect of oestrogen on the endometrium, therefore reducing the risk of endometrial cancer in women using HRT to relieve menopausal symptoms. Adding a progestin with an oestrogen is thought to help the feminisation process for male to female transsexuals and Microgest 100mg capsules are used as a component of transgender hormone therapy, to help stimulate the development breast development and reduce the production of testosterone.

How does Microgest work?

Microgest 100mg contains the female hormone progesterone, that is micronized, or reduced to tiny particles, so that it is better absorbed and can be taken orally as tablets. Endogenous progesterone is produced by the ovaries during the second phase of the menstrual cycle. It acts on the endometrium (lining of the uterus) converting the proliferating phase to the secretory phase. This causes the endometrium, which has thickened in response to oestrogen during the first half of the cycle, to stop growing and start secreting hormones and other proteins needed to maintain a pregnancy, if conception occurs; if not, levels of oestrogen and progesterone fall and the endometrium is shed (menstruation). When used for combination HRT, Microgest 100mg, containing micronized natural progesterone, works in the same way as natural progesterone and regulates endometrial growth in response to oestrogen, causing the thickened endometrium to be shed so that you will have a few days of withdrawal bleeding at the end of each month like a period. Microgest 100mg, reduces the risk of endometrial cancer which can be caused by oestrogen only HRT, without interfering with the beneficial effects of oestrogen, such as preventing bone loss and regulating cholesterol.

What does Microgest contain?

Microgest 100mg capsules contain a suspension of micronized progesterone in oil which is used to reduce the risk of endometrial (uterine) cancer which can develop in response to an oestrogen only HRT regime. Microgest 100mg capsules also contain peanut oil.

Microgest for hormone replacement therapy

Microgest 100mg capsules contains the female hormone progesterone, that is micronized, or reduced to tiny particles, and mixed with oil so that it is better absorbed and can be taken orally as tablets. Microgest 100mg capsules are used as part of a hormone replacement therapy (HRT) regime, to reduce the risk of endometrial (uterine) cancer, which can develop in response to an oestrogen only HRT regime. Taking oestrogen for HRT helps reduce symptoms of menopause caused by oestrogen deficiency, including, hot flushes, night sweats, sleeplessness, vaginal dryness, headaches, mood swings, lack of concentration and loss of energy. Oestrogen also has several other beneficial actions in various metabolic processes including bone turnover and lipid (fat) metabolism, but its effect of thickening the endometrium can lead to endometrial cancer in some menopausal women taking oestrogen only HRT. The micronized progesterone in Microgest 100mg capsules counteracts the effect of oestrogen and reduces the risk of endometrial cancer without interfering with the beneficial effects such as preventing bone loss and regulating cholesterol.

What is the difference between a natural progesterone like Microgest (micronized progesterone) and a synthetic progesterone (progestin)?

Microgest contains natural progesterone which is the female sex hormone belonging to the progestogen group, whereas progestins are synthetic progesterones which act in the same way as natural progesterone, but unlike natural progesterone they can be taken orally, as they are readily absorbed into the blood if swallowed as a tablet. Natural progesterone is not well absorbed in tablet form and until recently the only way to administer it was by injection. Micronized progesterone is natural progesterone reduced to tiny particles and mixed with oil so that it is better absorbed by the gastrointestinal system. Microgest 100mg contains micronized progesterone and is available for use as part of a hormone replacement therapy (HRT) regime to counteract the effect of oestrogen and reduce the risk of endometrial cancer without interfering with the beneficial effects, such as preventing bone loss and regulating cholesterol.

Microgest for transgender treatment

Microgest 100mg contains the female hormone progesterone, that is micronized, or reduced to tiny particles, and mixed with oil so that it is better absorbed and can be taken orally as tablets. Microgest 100mg capsules are used as a component of transgender hormone therapy for male to female transsexuals, to help stimulate the development of female sexual characteristics, such as breast development.

Microgest for feminising hormone therapy

Microgest 100mg capsules are used as a progestogen component of transgender hormone therapy along with the feminising hormone oestrogen, for male to female transsexuals, to help stimulate the development of female sexual characteristics, such as breast development.

What are the side effects of Microgest?

The most frequently reported side effects when taking Microgest 100mg tablets are drowsiness and sleepiness (which is why it is best taken at night). Other side effects include are breast tenderness and pain, abdominal bloating and pain, pre-menstrual symptoms, nausea, oedema, headache, skin rash and itching, insomnia and depression. More severe side effects include jaundice.

What are the health risks of Microgest?

Long-term hormone replacement therapy (HRT) with Microgest 100mg does have associated health risks, particularly increased risk of breast and ovarian cancer compared with oestrogen alone HRT, but it does reduce risk of endometrial cancer. Combined HRT with oestrogen and progestin therapy has been associated with an increased risk of cardiovascular events such as myocardial infarction and stroke, as well as venous thrombosis and pulmonary embolism.

When should Microgest not be used?

You should not use Microgest if you:
  • if you are allergic to peanuts as Microgest contains peanut oil and can cause an allergic reaction!!
  • have a past or family history of carcinoma of the breast, endometrial carcinoma or liver disease
  • have a history of thrombosis (blood clots) or stroke
  • have porphyria (a metabolic disease resulting in abnormal pigment in the urine and skin)
  • have abnormal genital bleeding of unknown cause
  • are pregnant or planning to become pregnant
  • are allergic to any of the ingredients in Microgest capsules
  • are taking other medications that may interact with Microgest, such as anticonvulsants like phenytoin and carbamazepin, anti-infectives like rifampicin, rifabutin, nevirapine, efavirenz, bromocriptine (for menstrual problems).

How should Microgest be taken?

You should take Microgest 100mg capsules with water but without food once a day preferably at bedtime, in addition to your usual oestrogen tablets, for the last 12 days of a 28-day cycle. Continue taking your Microgest 100mg capsules for as long as your doctor recommends.

How long should you take Microgest?

You should take Microgest 100mg capsules for the last 12 days of a 28-day cycle, in addition to your usual estrogen tablets, for as long as your doctor recommends, usually to coincide with a continuous 28 day cycle of oestrogen tablets.

Missed dose of Microgest

If you miss a dose of Microgest 100mg capsules, take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Microgest be stored?

Keep your Microgest 100mg capsules in the blister pack until use. The capsules are stable over a wide range of temperatures and therefore no special storage conditions are necessary.


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